IQCK - IQ motif containing K Gene
Species: Homo sapiens
About IQCK
This gene has 15 transcripts (splice variants) and 125 orthologues. Broad expression in brain (RPKM 34.9), testis (RPKM 17.8) and 17 other tissues.
Summary
This gene belongs to the IQ motif-containing family of proteins. The IQ motif serves as a binding site for different EF-hand proteins such as Calmodulin. This gene was identified as a potential candidate gene for obsessive-compulsive disorder in a genome-wide association study. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]
IQCK Products (6)
| mRNA | Protein | Name |
|---|---|---|
| NM_001305121.3 | NP_001292050.1 | IQ domain-containing protein K isoform 2 |
| NM_001305122.3 | NP_001292051.1 | IQ domain-containing protein K isoform 3 |
| NM_001394804.1 | NP_001381733.1 | IQ domain-containing protein K isoform 1 |
| NM_001394805.1 | NP_001381734.1 | IQ domain-containing protein K isoform 2 |
| NM_001394806.1 | NP_001381735.1 | IQ domain-containing protein K isoform 4 |
| NM_153208.3 | NP_694940.1 | IQ domain-containing protein K isoform 1 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
IQ domain-containing protein K |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Obsessive-Compulsive Disorder |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS06882 | IQCK Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Macaca mulatta | IQCK | VGNC | VGNC:73671 |
| Rattus norvegicus | IQCK | RGD | RGD:6502881 |
| Felis catus | IQCK | VGNC | VGNC:80585 |
| Bos taurus | IQCK | VGNC | VGNC:58601 |
| Mus musculus | IQCK | MGD | MGI:3612188 |
| Canis familiaris | IQCK | VGNC | VGNC:54037 |
| Others | IQCK | NCBI |
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