IQCK - IQ motif containing K Gene

Homo sapiens

Gene ID: 124152 | Gene type: protein coding

About IQCK

This gene has 15 transcripts (splice variants) and 125 orthologues. Broad expression in brain (RPKM 34.9), testis (RPKM 17.8) and 17 other tissues.

Summary

This gene belongs to the IQ motif-containing family of proteins. The IQ motif serves as a binding site for different EF-hand proteins such as Calmodulin. This gene was identified as a potential candidate gene for obsessive-compulsive disorder in a genome-wide association study. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]

IQCK Products(6)

mRNA	Protein	Name
NM_001305121.3	NP_001292050.1	IQ domain-containing protein K isoform 2
NM_001305122.3	NP_001292051.1	IQ domain-containing protein K isoform 3
NM_001394804.1	NP_001381733.1	IQ domain-containing protein K isoform 1
NM_001394805.1	NP_001381734.1	IQ domain-containing protein K isoform 2
NM_001394806.1	NP_001381735.1	IQ domain-containing protein K isoform 4
NM_153208.3	NP_694940.1	IQ domain-containing protein K isoform 1

Protein Preferred Names

Protein Names

IQ domain-containing protein K

Related Diseases

Diseases

Alias

Obsessive-Compulsive Disorder

OCD	Obsessive-Compulsive Disorder, Susceptibility To
Anancastic Neurosis	Obsessive Compulsive Disorder
Anankastic Neurosis	Obsessive-Compulsive Neurosis
Obsessive Compulsive Behavior

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06882	IQCK Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	IQCK	VGNC	VGNC:73671
Rattus norvegicus	IQCK	RGD	RGD:6502881
Felis catus	IQCK	VGNC	VGNC:80585
Bos taurus	IQCK	VGNC	VGNC:58601
Mus musculus	IQCK	MGD	MGI:3612188
Canis familiaris	IQCK	VGNC	VGNC:54037