Cdk5r2 - cyclin-dependent kinase 5, regulatory subunit 2 (p39) Gene

Also Known as p39; B230310J22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12570

Summary

Enables actin binding activity and cyclin-dependent protein serine/threonine kinase activator activity. Acts upstream of or within nervous system development; positive regulation of calcium ion-dependent exocytosis; and positive regulation of protein kinase activity. Located in cytoplasm. Is expressed in several structures, including nervous system and retina. Orthologous to human CDK5R2 (cyclin dependent kinase 5 regulatory subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Cdk5r2 Products (1)

mRNA Protein Name
NM_009872.3 NP_034002.2 cyclin-dependent kinase 5 activator 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actin binding IPI
IPI: Inferred from physical interaction
10683146 MGI
enables cyclin-dependent protein serine/threonine kinase activator activity IDA
IDA: Inferred from direct assay
10683146 MGI
enables cyclin-dependent protein serine/threonine kinase activator activity IMP
IMP: Inferred from mutant phenotype
11517264 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cerebellum development IGI
IGI: Inferred from genetic interaction
11517264 MGI
acts upstream of or within hippocampus development IGI
IGI: Inferred from genetic interaction
11517264 MGI
acts upstream of or within layer formation in cerebral cortex IGI
IGI: Inferred from genetic interaction
11517264 MGI
acts upstream of or within neuron migration IGI
IGI: Inferred from genetic interaction
11517264 MGI
acts upstream of or within positive regulation of calcium ion-dependent exocytosis IDA
IDA: Inferred from direct assay
15123626 MGI
acts upstream of or within positive regulation of protein kinase activity IGI
IGI: Inferred from genetic interaction
11517264 MGI
acts upstream of or within superior olivary nucleus maturation IGI
IGI: Inferred from genetic interaction
11517264 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15123626 MGI
is active in presynapse IDA
IDA: Inferred from direct assay
10923673 MGI
is active in presynapse IEP
IEP: Inferred from expression pattern
10923673 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cyclin-dependent kinase 5 activator 2

  • CDK5 activator 2

  • cyclin-dependent kinase 5 regulatory subunit 2

  • p39I

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02388 CDK5R2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdk5r2 NCBI NCBI:8941