PODN - podocan Gene

Homo sapiens

Also known as PCAN; SLRR5A

Gene ID: 127435 | Gene type: protein coding

About PODN

Cytogenetic location: 1p32.3 Genomic coordinates (GRCh38): 1:53,062,213-53,085,494 (from NCBI)

This gene has 9 transcripts (splice variants), 193 orthologues and 22 paralogues. Broad expression in gall bladder (RPKM 52.1), ovary (RPKM 37.5) and 19 other tissues.

Summary

The protein encoded by this gene is a member of the small leucine-rich repeat protein family and contains an amino terminal CX3CXCX7C cysteine-rich cluster followed by a leucine-rich repeat domain. Studies suggest that this protein could function to inhibit smooth muscle cell proliferation and migration following arterial injury. [provided by RefSeq, Jul 2016]

PODN Products(3)

mRNA	Protein	Name
NM_001199080.4	NP_001186009.2	podocan precursor
NM_001199081.3	NP_001186010.2	podocan precursor
NM_153703.5	NP_714914.3	podocan precursor

PODN Protein Structure

LRR_8

LRR_1

LRR_8

0
200
400
600
661 a.a.

Protein Preferred Names

Protein Names

podocan

podocan proteoglycan

Related Diseases

Diseases

Alias

Joubert Syndrome 9

JBTS9

Joubert Syndrome, Type 9

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10807	PODN Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	PODN	VGNC	VGNC:33101
Felis catus	PODN	VGNC	VGNC:64273
Rattus norvegicus	PODN	RGD	RGD:7545693
Canis familiaris	PODN	VGNC	VGNC:44763
Macaca mulatta	PODN	VGNC	VGNC:76096
Mus musculus	PODN	MGD	MGI:2674939