2. Gene
  3. Clta - clathrin, light polypeptide (Lca) Gene

Clta - clathrin, light polypeptide (Lca) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Lca

Gene ID: 12757 | Gene type: protein coding

About Clta

Summary

Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Clta Products(9)

mRNA Protein Name
NM_001080384.3 NP_001073853.1 clathrin light chain A isoform a
NM_001080385.2 NP_001073854.1 clathrin light chain A isoform b
NM_001080386.2 NP_001073855.1 clathrin light chain A isoform d
NM_001290470.2 NP_001277399.1 clathrin light chain A isoform e
NM_001369156.1 NP_001356085.1 clathrin light chain A isoform f
NM_001369157.1 NP_001356086.1 clathrin light chain A isoform g
NM_001369158.1 NP_001356087.1 clathrin light chain A isoform h
NM_001369159.1 NP_001356088.1 clathrin light chain A isoform i
NM_016760.3 NP_058040.2 clathrin light chain A isoform c
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
20730103 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
17880892 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
17880892 MGI
is active in postsynaptic endocytic zone IDA
IDA: Inferred from direct assay
17880892 MGI
is active in postsynaptic endocytic zone IMP
IMP: Inferred from mutant phenotype
17880892 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

clathrin light chain A

clathryn light chain (LCA2)

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02843 CLTA Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Clta NCBI NCBI:1211