Cnga1 - cyclic nucleotide gated channel alpha 1 Gene

Also Known as Cncg

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12788

Summary

Predicted to enable cGMP binding activity; intracellular cAMP-activated cation channel activity; and intracellular cGMP-activated cation channel activity. Predicted to be involved in membrane depolarization and regulation of cytosolic calcium ion concentration. Predicted to act upstream of or within ion transport and visual perception. Located in photoreceptor outer segment membrane. Is expressed in photoreceptor layer outer segment; retina; and retina outer nuclear layer. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 49. Orthologous to human CNGA1 (cyclic nucleotide gated channel subunit alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Cnga1 Products (1)

mRNA Protein Name
NM_007723.2 NP_031749.2 cGMP-gated cation channel alpha-1

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in membrane IDA
IDA: Inferred from direct assay
15634774 MGI
located in photoreceptor outer segment IDA
IDA: Inferred from direct assay
10725384 MGI
located in photoreceptor outer segment membrane IDA
IDA: Inferred from direct assay
18654668 MGI
located in rod photoreceptor outer segment IDA
IDA: Inferred from direct assay
22802073 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cGMP-gated cation channel alpha-1

  • CNG channel alpha-1

  • CNG-1

  • CNG1

  • cyclic nucleotide gated channel, cGMP gated

  • cyclic nucleotide-gated cation channel 1

  • cyclic nucleotide-gated channel, photoreceptor

  • rod photoreceptor cGMP-gated channel subunit alpha

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02879 CNGA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cnga1 NCBI NCBI:1259