NKAIN4 - sodium/potassium transporting ATPase interacting 4 Gene

Also Known as FAM77A; C20orf58; bA261N11.2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 128414

About NKAIN4

Cytogenetic location: 20q13.33 Genomic coordinates (GRCh38): 20:63,240,784-63,254,921 (from NCBI)

This gene has 9 transcripts (splice variants), 250 orthologues and 3 paralogues. Biased expression in brain (RPKM 15.5), kidney (RPKM 2.4) and 1 other tissue.

Summary

NKAIN4 is a member of a family of mammalian proteins (see NKAIN1; MIM 612871) with similarity to Drosophila Nkain and interacts with the beta subunit of Na,K-ATPase (ATP1B1; MIM 182330) (Gorokhova et al., 2007 [PubMed 17606467]).[supplied by OMIM, Jun 2009]

NKAIN4 Products (3)

mRNA Protein Name
NM_001363718.1 NP_001350647.1 sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4 isoform 2
NM_001363747.1 NP_001350676.1 sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4 isoform 3
NM_152864.4 NP_690603.3 sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4 isoform 1 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NKAIN4 Protein Structure

NKAIN

NKAIN: Na,K-Atpase Interacting protein (1 - 187)

  • 0
  • 100
  • 208 a.a.
Protein Preferred Names Protein Names

sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4

  • Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09314 NKAIN4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris NKAIN4 VGNC VGNC:43825
Rattus norvegicus NKAIN4 RGD RGD:1305809
Mus musculus NKAIN4 MGD MGI:1915372
Macaca mulatta NKAIN4 VGNC VGNC:75184
Others NKAIN4 NCBI