Cpeb1 - cytoplasmic polyadenylation element binding protein 1 Gene

Also Known as Cpeb; mCPEB; Cpe-bp1; mCpeb-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12877

Summary

Enables mRNA 3'-UTR AU-rich region binding activity and translation repressor activity, mRNA regulatory element binding. Involved in cellular response to amino acid stimulus; cellular response to hypoxia; and negative regulation of cytoplasmic translation. Acts upstream of or within regulation of neuronal synaptic plasticity; regulation of translation; and synaptonemal complex assembly. Located in several cellular components, including cytoplasm; meiotic spindle; and nucleus. Is expressed in brain; early embryo; olfactory epithelium; and reproductive system. Orthologous to human CPEB1 (cytoplasmic polyadenylation element binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Cpeb1 Products (19)

mRNA Protein Name
NM_001252525.1 NP_001239454.1 cytoplasmic polyadenylation element-binding protein 1 isoform 1
NM_001252526.1 NP_001239455.1 cytoplasmic polyadenylation element-binding protein 1 isoform 3
NM_001357107.1 NP_001344036.1 cytoplasmic polyadenylation element-binding protein 1 isoform 4
NM_001412273.1 NP_001399202.1 cytoplasmic polyadenylation element-binding protein 1 isoform 5
NM_001412274.1 NP_001399203.1 cytoplasmic polyadenylation element-binding protein 1 isoform 6
NM_001412275.1 NP_001399204.1 cytoplasmic polyadenylation element-binding protein 1 isoform 7
NM_001412276.1 NP_001399205.1 cytoplasmic polyadenylation element-binding protein 1 isoform 8
NM_001412277.1 NP_001399206.1 cytoplasmic polyadenylation element-binding protein 1 isoform 9
NM_001412278.1 NP_001399207.1 cytoplasmic polyadenylation element-binding protein 1 isoform 9
NM_001412279.1 NP_001399208.1 cytoplasmic polyadenylation element-binding protein 1 isoform 9
NM_001412280.1 NP_001399209.1 cytoplasmic polyadenylation element-binding protein 1 isoform 4
NM_001412281.1 NP_001399210.1 cytoplasmic polyadenylation element-binding protein 1 isoform 4
NM_001412282.1 NP_001399211.1 cytoplasmic polyadenylation element-binding protein 1 isoform 4
NM_001412283.1 NP_001399212.1 cytoplasmic polyadenylation element-binding protein 1 isoform 4
NM_001412284.1 NP_001399213.1 cytoplasmic polyadenylation element-binding protein 1 isoform 4
NM_001412285.1 NP_001399214.1 cytoplasmic polyadenylation element-binding protein 1 isoform 10
NM_001412286.1 NP_001399215.1 cytoplasmic polyadenylation element-binding protein 1 isoform 10
NM_001412287.1 NP_001399216.1 cytoplasmic polyadenylation element-binding protein 1 isoform 10
NM_007755.5 NP_031781.1 cytoplasmic polyadenylation element-binding protein 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA binding IDA
IDA: Inferred from direct assay
17024188 MGI
enables mRNA 3'-UTR AU-rich region binding IDA
IDA: Inferred from direct assay
18752464 MGI
enables mRNA binding IDA
IDA: Inferred from direct assay
11702780 MGI
enables mRNA regulatory element binding translation repressor activity IDA
IDA: Inferred from direct assay
18752464 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16314516 MGI
Biological Process GO Annotation Evidence References Source
involved in cellular response to amino acid stimulus IDA
IDA: Inferred from direct assay
20937770 MGI
involved in cellular response to hypoxia IDA
IDA: Inferred from direct assay
18752464 MGI
involved in negative regulation of cytoplasmic translation IDA
IDA: Inferred from direct assay
18752464 MGI
acts upstream of or within regulation of neuronal synaptic plasticity IMP
IMP: Inferred from mutant phenotype
15169862 MGI
acts upstream of or within regulation of translation IDA
IDA: Inferred from direct assay
11702780 MGI
involved in regulation of translation at synapse, modulating synaptic transmission IDA
IDA: Inferred from direct assay
18716208 MGI
involved in regulation of translation at synapse, modulating synaptic transmission IMP
IMP: Inferred from mutant phenotype
18716208 MGI
acts upstream of or within synaptonemal complex assembly IMP
IMP: Inferred from mutant phenotype
11702780 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
20937770 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
18716208 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
18716208 MGI
located in meiotic spindle IDA
IDA: Inferred from direct assay
20668163 MGI
located in membrane IDA
IDA: Inferred from direct assay
16314516 MGI
located in nucleus IDA
IDA: Inferred from direct assay
20937770 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytoplasmic polyadenylation element-binding protein 1

  • CPE-binding protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-145944 ASR-488 Inducer 99.73% Unkown
HY-RS03091 CPEB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cpeb1 NCBI NCBI:64506