2. Gene
  3. Cryba1 - crystallin, beta A1 Gene

Cryba1 - crystallin, beta A1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cryb; BA3/A1

Gene ID: 12957 | Gene type: protein coding

About Cryba1

Summary

Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with Other beta-crystallins. This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a single mRNA. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

Cryba1 Products(2)

mRNA Protein Name
NM_001313933.1 NP_001300862.1 beta-crystallin A1 isoform 2
NM_009965.3 NP_034095.1 beta-crystallin A1 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
14717595 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within camera-type eye development IMP
IMP: Inferred from mutant phenotype
10585769 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

beta-crystallin A1

beta-A1-crystallin

beta-A3/A1-crystallin

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03208 CRYBA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cryba1 NCBI NCBI:1411