Crygb - crystallin, gamma B Gene

Also Known as Nop; Cryg-3; DGcry-3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12965

Summary

A structural constituent of eye lens. Acts upstream of or within lens fiber cell morphogenesis. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system and eye. Used to study cataract 39 multiple types. Human ortholog(s) of this gene implicated in cataract 39 multiple types. Orthologous to human CRYGB (crystallin gamma B). [provided by Alliance of Genome Resources, Apr 2022]

Crygb Products (1)

mRNA Protein Name
NM_144761.2 NP_658906.1 gamma-crystallin B

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables structural constituent of eye lens IDA
IDA: Inferred from direct assay
12426373 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within eye development IMP
IMP: Inferred from mutant phenotype
15037589 MGI
acts upstream of or within lens development in camera-type eye IMP
IMP: Inferred from mutant phenotype
8626090 MGI
acts upstream of or within lens fiber cell development IMP
IMP: Inferred from mutant phenotype
18172107 MGI
acts upstream of or within lens fiber cell morphogenesis IMP
IMP: Inferred from mutant phenotype
8626090 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
12426373 MGI
located in nucleus IDA
IDA: Inferred from direct assay
12426373 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gamma-crystallin B

  • gamma-B-crystallin

  • gamma-crystallin 3

  • gammaB-crystallin

  • nuclear opacity

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03213 CRYGB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Crygb NCBI NCBI:1419