Pcyt1a - phosphate cytidylyltransferase 1, choline, alpha isoform Gene

Also Known as Ctpct; CTalpha; Cctalpha; Cttalpha

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13026

Summary

Enables choline-phosphate cytidylyltransferase activity. Involved in CDP-choline pathway. Located in endoplasmic reticulum membrane and glycogen granule. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in spondylometaphyseal dysplasia with cone-rod dystrophy. Orthologous to human PCYT1A (phosphate cytidylyltransferase 1A, choline). [provided by Alliance of Genome Resources, Apr 2022]

Pcyt1a Products (3)

mRNA Protein Name
NM_001163159.1 NP_001156631.1 choline-phosphate cytidylyltransferase A
NM_001163160.1 NP_001156632.1 choline-phosphate cytidylyltransferase A
NM_009981.4 NP_034111.1 choline-phosphate cytidylyltransferase A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables choline-phosphate cytidylyltransferase activity IDA
IDA: Inferred from direct assay
12842190 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
21343341 MGI
Biological Process GO Annotation Evidence References Source
involved in B cell proliferation IMP
IMP: Inferred from mutant phenotype
19139091 MGI
involved in CDP-choline pathway IDA
IDA: Inferred from direct assay
12842190 MGI
involved in isotype switching IMP
IMP: Inferred from mutant phenotype
19139091 MGI
acts upstream of or within phosphatidylcholine biosynthetic process IDA
IDA: Inferred from direct assay
11829742 MGI
involved in phosphatidylcholine biosynthetic process IDA
IDA: Inferred from direct assay
12842190 MGI
acts upstream of or within phosphatidylcholine biosynthetic process IMP
IMP: Inferred from mutant phenotype
15798219 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
15169678 MGI
located in glycogen granule IDA
IDA: Inferred from direct assay
15169678 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

choline-phosphate cytidylyltransferase A

  • CCT A

  • CCT-alpha

  • CT A

  • CTP phosphocholine cytidylyl transferase

  • CTP:phosphocholine cytidylyltransferase A

  • CTP:phosphocholine cytidylyltransferase alpha

  • phosphorylcholine transferase A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10180 PCYT1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pcyt1a NCBI NCBI:5130