2. Gene
  3. Pcbd1 - pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1 Gene

Pcbd1 - pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Pcd; Phs; Dcoh; Pcbd

Gene ID: 13180 | Gene type: protein coding

About Pcbd1

Summary

This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. [provided by RefSeq, Apr 2015]

Pcbd1 Products(1)

mRNA Protein Name
NM_025273.4 NP_079549.1 pterin-4-alpha-carbinolamine dehydratase
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
15182178 MGI
enables phenylalanine 4-monooxygenase activity IDA
IDA: Inferred from direct assay
15182178 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15182178 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IPI
IPI: Inferred from physical interaction
15182178 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pterin-4-alpha-carbinolamine dehydratase

4-alpha-hydroxy-tetrahydropterin dehydratase

6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)

dimerization cofactor of HNF1

phenylalanine hydroxylase-stimulating protein

pterin carbinolamine dehydr

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10113 PCBD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pcbd1 NCBI NCBI:5092