2. Gene
  3. Defa6 - defensin, alpha, 6 Gene

Defa6 - defensin, alpha, 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Defcr6

Gene ID: 13240 | Gene type: protein coding

About Defa6

Summary

Predicted to enable protein homodimerization activity. Acts upstream of or within response to bacterium and response to xenobiotic stimulus. Located in extracellular space. Orthologous to human DEFA3 (defensin alpha 3); DEFA5 (defensin alpha 5); and DEFA6 (defensin alpha 6). [provided by Alliance of Genome Resources, Apr 2022]

Defa6 Products(1)

mRNA Protein Name
NM_007852.1 NP_031878.1 alpha-defensin 6/12 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to lipopolysaccharide IGI
IGI: Inferred from genetic interaction
11248802 MGI
acts upstream of or within defense response to Gram-negative bacterium IGI
IGI: Inferred from genetic interaction
11248802 MGI
acts upstream of or within defense response to Gram-positive bacterium IGI
IGI: Inferred from genetic interaction
11248802 MGI
acts upstream of or within defense response to bacterium IDA
IDA: Inferred from direct assay
7927786 MGI
acts upstream of or within response to xenobiotic stimulus IDA
IDA: Inferred from direct assay
11248802 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
11248802 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-defensin 6/12

alpha-defensin, 6

cryptdin-2

defensin related cryptdin 6

defensin-related cryptdin-6/12

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03677 DEFA6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Defa6 NCBI NCBI:1671