Dffb - DNA fragmentation factor, beta subunit Gene

Also Known as CAD; CPAN; 40kDa; DFF40; Didff; 5730477D02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13368

Summary

Enables DNA binding activity and nuclease activity. Predicted to be involved in apoptotic DNA fragmentation and apoptotic chromosome condensation. Predicted to be located in chromatin; cytosol; and nuclear lumen. Predicted to be part of protein-containing complex. Orthologous to human DFFB (DNA fragmentation factor subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Dffb Products (1)

mRNA Protein Name
NM_007859.4 NP_031885.3 DNA fragmentation factor subunit beta

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
15572351 MGI
enables nuclease activity IDA
IDA: Inferred from direct assay
15572351 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
14557248 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA fragmentation factor subunit beta

  • DFF-40

  • DNA fragmentation factor 40 kDa subunit

  • DNA fragmentation factor, 40 kD, beta subunit

  • DNase inhibited by DNA fragmentation factor

  • caspase-activated DNase

  • caspase-activated deoxyribonuclease

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03709 DFFB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dffb NCBI NCBI:1677