2. Gene
  3. Dffb - DNA fragmentation factor, beta subunit Gene

Dffb - DNA fragmentation factor, beta subunit Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as CAD; CPAN; 40kDa; DFF40; Didff; 5730477D02Rik

Gene ID: 13368 | Gene type: protein coding

About Dffb

Summary

Enables DNA binding activity and nuclease activity. Predicted to be involved in apoptotic DNA fragmentation and apoptotic chromosome condensation. Predicted to be located in chromatin; cytosol; and nuclear lumen. Predicted to be part of protein-containing complex. Orthologous to human DFFB (DNA fragmentation factor subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Dffb Products(1)

mRNA Protein Name
NM_007859.4 NP_031885.3 DNA fragmentation factor subunit beta
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables DNA binding IDA
IDA: Inferred from direct assay
15572351 MGI
enables nuclease activity IDA
IDA: Inferred from direct assay
15572351 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
14557248 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA fragmentation factor subunit beta

DFF-40

DNA fragmentation factor 40 kDa subunit

DNA fragmentation factor, 40 kD, beta subunit

DNase inhibited by DNA fragmentation factor

caspase-activated DNase

caspase-activated deoxyribonuclease

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03709 DFFB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dffb NCBI NCBI:1677