Dlx6 - distal-less homeobox 6 Gene

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including embryonic morphogenesis; positive regulation of epithelial cell proliferation; and roof of mouth development. Predicted to be located in nucleus. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; limb; and sensory organ. Used to study split hand-foot malformation 1. Orthologous to human DLX6 (distal-less homeobox 6). [provided by Alliance of Genome Resources, Apr 2022]