Dnase2a - deoxyribonuclease II alpha Gene

Also Known as Dnase2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13423

Summary

Enables deoxyribonuclease II activity. Acts upstream of or within DNA catabolic process, endonucleolytic; erythrocyte differentiation; and regulation of immune response. Predicted to be located in lysosome. Is expressed in olfactory epithelium and vibrissa. Used to study rheumatoid arthritis. Orthologous to human DNASE2 (deoxyribonuclease 2, lysosomal). [provided by Alliance of Genome Resources, Apr 2022]

Dnase2a Products (3)

mRNA Protein Name
NM_001368295.1 NP_001355224.1 deoxyribonuclease-2-alpha isoform 3 precursor
NM_001368296.1 NP_001355225.1 deoxyribonuclease-2-alpha isoform 2
NM_010062.4 NP_034192.1 deoxyribonuclease-2-alpha isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables deoxyribonuclease II activity IDA
IDA: Inferred from direct assay
11375492 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within DNA catabolic process IMP
IMP: Inferred from mutant phenotype
15568025 MGI
acts upstream of or within enucleate erythrocyte differentiation IMP
IMP: Inferred from mutant phenotype
11375492 MGI
acts upstream of or within regulation of immune response IGI
IGI: Inferred from genetic interaction
26371324 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

deoxyribonuclease-2-alpha

  • DNase II alpha

  • acid DNase

  • lysosomal DNase II

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03898 DNASE2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28363 Dnase2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown