Dync1i2 - dynein cytoplasmic 1 intermediate chain 2 Gene

Also Known as Dncic2; 3110079H08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13427

Summary

Predicted to enable dynein heavy chain binding activity and dynein light chain binding activity. Predicted to be involved in negative regulation of neuron projection development and transport along microtubule. Part of outer dynein arm. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; limb bud; and nose. Orthologous to human DYNC1I2 (dynein cytoplasmic 1 intermediate chain 2). [provided by Alliance of Genome Resources, Apr 2022]

Dync1i2 Products (9)

mRNA Protein Name
NM_001198872.1 NP_001185801.1 cytoplasmic dynein 1 intermediate chain 2 isoform 1
NM_001198873.1 NP_001185802.1 cytoplasmic dynein 1 intermediate chain 2 isoform 2
NM_001198874.1 NP_001185803.1 cytoplasmic dynein 1 intermediate chain 2 isoform 3
NM_001198875.1 NP_001185804.1 cytoplasmic dynein 1 intermediate chain 2 isoform 4
NM_001198876.1 NP_001185805.1 cytoplasmic dynein 1 intermediate chain 2 isoform 5
NM_001198877.1 NP_001185806.1 cytoplasmic dynein 1 intermediate chain 2 isoform 1
NM_001198878.1 NP_001185807.1 cytoplasmic dynein 1 intermediate chain 2 isoform 2
NM_001347173.1 NP_001334102.1 cytoplasmic dynein 1 intermediate chain 2 isoform 6
NM_010064.4 NP_034194.1 cytoplasmic dynein 1 intermediate chain 2 isoform 5

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22956769 MGI
Cellular Component GO Annotation Evidence References Source
part of outer dynein arm IDA
IDA: Inferred from direct assay
27353389 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytoplasmic dynein 1 intermediate chain 2

  • DH IC-2

  • dynein intermediate chain 2, cytosolic

  • dynein, cytoplasmic, intermediate chain 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04084 DYNC1I2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dync1i2 NCBI NCBI:1781