Doc2a - double C2, alpha Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13446

Summary

Predicted to enable calcium ion binding activity and calcium-dependent phospholipid binding activity. Involved in regulation of calcium ion-dependent exocytosis. Acts upstream of or within spontaneous neurotransmitter secretion. Predicted to be located in cell junction; lysosome; and nuclear lumen. Is expressed in cerebral cortex. Orthologous to human DOC2A (double C2 domain alpha). [provided by Alliance of Genome Resources, Apr 2022]

Doc2a Products (6)

mRNA Protein Name
NM_001368355.1 NP_001355284.1 double C2-like domain-containing protein alpha
NM_001368356.2 NP_001355285.1 double C2-like domain-containing protein alpha
NM_001368357.1 NP_001355286.1 double C2-like domain-containing protein alpha
NM_001368358.1 NP_001355287.1 double C2-like domain-containing protein alpha
NM_001412324.1 NP_001399253.1 double C2-like domain-containing protein alpha
NM_010069.2 NP_034199.1 double C2-like domain-containing protein alpha

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in calcium-dependent activation of synaptic vesicle fusion IDA
IDA: Inferred from direct assay
20150444 MGI
involved in calcium-dependent activation of synaptic vesicle fusion IMP
IMP: Inferred from mutant phenotype
20150444 MGI
involved in regulation of calcium ion-dependent exocytosis IMP
IMP: Inferred from mutant phenotype
18354201 MGI
acts upstream of or within spontaneous neurotransmitter secretion IDA
IDA: Inferred from direct assay
21521611 MGI
acts upstream of or within spontaneous neurotransmitter secretion IGI
IGI: Inferred from genetic interaction
21521611 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

double C2-like domain-containing protein alpha

  • doc2-alpha

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03919 DOC2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Doc2a NCBI NCBI:8448