1. Gene
  2. Dsg1a - desmoglein 1 alpha Gene

Dsg1a - desmoglein 1 alpha Gene

Mus musculus

Also known as DG1; DGI; Dsg1; dsg1-alpha

Gene ID: 13510 | Gene type: protein coding

About Dsg1a

Summary

This gene encodes a member of the Cadherin family of proteins that forms an integral transmembrane component of desmosomes, the multiprotein complexes involved in cell adhesion, organization of the Cytoskeleton, cell sorting and cell signaling. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. This gene is located in a cluster of desmosomal Cadherin genes on chromosome 18. [provided by RefSeq, Jan 2016]

Dsg1a Products(1)

mRNA Protein Name
NM_010079.2 NP_034209.2 desmoglein-1-alpha preproprotein
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12847106 MGI
Cellular Component GO Annotation Evidence Reference Source
located in desmosome IDA
IDA: Inferred from direct assay
12631242 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
12093888 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

desmoglein-1-alpha

desmosomal glycoprotein I