HINT3 - histidine triad nucleotide binding protein 3 Gene

Also Known as HINT4

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 135114

About HINT3

Cytogenetic location: 6q22.32 Genomic coordinates (GRCh38): 6:125,956,770-125,980,244 (from NCBI)

This gene has 1 transcript (splice variant), 199 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 18.9), prostate (RPKM 17.5) and 25 other tissues.

Summary

Histidine triad proteins, such as HINT3, are nucleotide hydrolases and transferases that act on the alpha-phosphate of ribonucleotides (Brenner, 2002 [PubMed 12119013]).[supplied by OMIM, Mar 2008]

HINT3 Products (1)

mRNA Protein Name
NM_138571.5 NP_612638.3 adenosine 5'-monophosphoramidase HINT3

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables adenosine 5'-monophosphoramidase activity IDA
IDA: Inferred from direct assay
17870088 GOA
enables identical protein binding IDA
IDA: Inferred from direct assay
17870088 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IMP
IMP: Inferred from mutant phenotype
17870088 GOA
located in nucleus IMP
IMP: Inferred from mutant phenotype
17870088 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HINT3 Protein Structure

DcpS_C

DcpS_C: Scavenger mRNA decapping enzyme C-term binding (48 - 154)

  • 0
  • 100
  • 182 a.a.
Protein Preferred Names Protein Names

adenosine 5'-monophosphoramidase HINT3

  • HINT-3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06178 HINT3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus HINT3 MGD MGI:1914097
Bos taurus HINT3 VGNC VGNC:29856
Macaca mulatta HINT3 VGNC VGNC:73413
Canis familiaris HINT3 VGNC VGNC:41690
Rattus norvegicus HINT3 RGD RGD:621603
Felis catus HINT3 VGNC VGNC:102439
Others HINT3 NCBI