Efs - embryonal Fyn-associated substrate Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13644

Summary

Enables SH3 domain binding activity. Predicted to be involved in actin filament reorganization; cell migration; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to act upstream of or within cell adhesion. Predicted to be active in cytoplasm and focal adhesion. Predicted to colocalize with plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and integumental system. Used to study Crohn's disease. Orthologous to human EFS (embryonal Fyn-associated substrate). [provided by Alliance of Genome Resources, Apr 2022]

Efs Products (1)

mRNA Protein Name
NM_010112.4 NP_034242.2 embryonal Fyn-associated substrate

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables SH3 domain binding IDA
IDA: Inferred from direct assay
9126384 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

embryonal Fyn-associated substrate

  • SRC-interacting protein

  • signal-integrating protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-174257 RCD405 Inhibitor / Unkown
HY-RS04202 EFS Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Efs NCBI NCBI:10278