Egr3 - early growth response 3 Gene

Also Known as EGR-3; Pilot

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13655

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within neuromuscular synaptic transmission; peripheral nervous system development; and regulation of T cell differentiation. Predicted to be located in nucleoplasm. Is expressed in genitourinary system; limb mesenchyme; limb musculature; tooth; and vibrissa. Orthologous to human EGR3 (early growth response 3). [provided by Alliance of Genome Resources, Apr 2022]

Egr3 Products (6)

mRNA Protein Name
NM_001289925.2 NP_001276854.1 early growth response protein 3 isoform 2
NM_001289927.1 NP_001276856.1 early growth response protein 3 isoform 3
NM_018781.4 NP_061251.1 early growth response protein 3 isoform 1
NM_001289925.2 NP_001276854.1 early growth response protein 3 isoform 2
NM_001289927.1 NP_001276856.1 early growth response protein 3 isoform 3
NM_018781.4 NP_061251.1 early growth response protein 3 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
14560009 MGI
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
23332764 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within neuromuscular synaptic transmission IMP
IMP: Inferred from mutant phenotype
11978828 MGI
acts upstream of or within peripheral nervous system development IMP
IMP: Inferred from mutant phenotype
15582775 MGI
acts upstream of or within positive regulation of T cell differentiation in thymus IMP
IMP: Inferred from mutant phenotype
21737317 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
14560009 MGI
acts upstream of or within regulation of gamma-delta T cell differentiation IDA
IDA: Inferred from direct assay
21737317 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

early growth response protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P2096 Hexapeptide-11 99.77% Unkown
HY-RS04217 EGR3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19895 Egr3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26396 Egr3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W106688 Triisopropyl phosphate Antagonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Egr3 NCBI NCBI:1960