1. Gene
  2. Eif2b4 - eukaryotic translation initiation factor 2B, subunit 4 delta Gene

Eif2b4 - eukaryotic translation initiation factor 2B, subunit 4 delta Gene

Mus musculus

Also known as Eif2b

Gene ID: 13667 | Gene type: protein coding

About Eif2b4

Summary

Predicted to enable translation initiation factor binding activity. Predicted to contribute to guanyl-nucleotide exchange factor activity and translation initiation factor activity. Predicted to be involved in several processes, including T cell receptor signaling pathway; negative regulation of guanyl-nucleotide exchange factor activity; and nervous system development. Predicted to act upstream of or within translation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 2B complex. Is expressed in several structures, including adipose tissue; brain; eye; gut gland; and male reproductive gland or organ. Used to study leukoencephalopathy with vanishing white matter. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter. Orthologous to human EIF2B4 (eukaryotic translation initiation factor 2B subunit delta). [provided by Alliance of Genome Resources, Apr 2022]

Eif2b4 Products(3)

mRNA Protein Name
NM_001127355.1 NP_001120827.1 translation initiation factor eIF-2B subunit delta isoform 1
NM_001127356.1 NP_001120828.1 translation initiation factor eIF-2B subunit delta isoform 1
NM_010122.2 NP_034252.2 translation initiation factor eIF-2B subunit delta isoform 2
Protein Preferred Names Protein Names

translation initiation factor eIF-2B subunit delta

eIF-2B GDP-GTP exchange factor subunit delta

Orthologs Information

Species Symbol Source ID
Homo sapiens Eif2b4 NCBI NCBI:8890