Emx1 - empty spiracles homeobox 1 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13796

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including nervous system development; neuroepithelial cell differentiation; and regulation of oligodendrocyte progenitor proliferation. Located in nucleus. Is expressed in several structures, including genitourinary system; ileum; nervous system; sensory organ; and surface ectoderm. Orthologous to human EMX1 (empty spiracles homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Emx1 Products (1)

mRNA Protein Name
NM_010131.2 NP_034261.1 homeobox protein EMX1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
29263200 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within brain development IMP
IMP: Inferred from mutant phenotype
12091317 MGI
acts upstream of or within brain morphogenesis IGI
IGI: Inferred from genetic interaction
23178126 MGI
acts upstream of or within cerebral cortex development IGI
IGI: Inferred from genetic interaction
12764040 MGI
acts upstream of or within cerebral cortex development IMP
IMP: Inferred from mutant phenotype
16892058 MGI
acts upstream of or within cerebral cortex neuron differentiation IGI
IGI: Inferred from genetic interaction
23178126 MGI
acts upstream of or within cerebral cortex regionalization IGI
IGI: Inferred from genetic interaction
15147765 MGI
acts upstream of or within homeostasis of number of cells IGI
IGI: Inferred from genetic interaction
25100583 MGI
acts upstream of or within in utero embryonic development IGI
IGI: Inferred from genetic interaction
23861879 MGI
acts upstream of or within neuroepithelial cell differentiation IGI
IGI: Inferred from genetic interaction
25100583 MGI
acts upstream of or within neuron differentiation IMP
IMP: Inferred from mutant phenotype
12561075 MGI
acts upstream of or within neuron projection extension IGI
IGI: Inferred from genetic interaction
23861879 MGI
acts upstream of or within post-embryonic development IMP
IMP: Inferred from mutant phenotype
16892058 MGI
acts upstream of or within radial glial cell differentiation IGI
IGI: Inferred from genetic interaction
25100583 MGI
acts upstream of or within regulation of oligodendrocyte progenitor proliferation IGI
IGI: Inferred from genetic interaction
25100583 MGI
acts upstream of or within response to xenobiotic stimulus IDA
IDA: Inferred from direct assay
9098922 MGI
acts upstream of or within telencephalon development IGI
IGI: Inferred from genetic interaction
25100583 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
29263200 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein EMX1

  • empty spiracles homolog 1

  • empty spiracles-like protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04363 EMX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21335 Emx1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27854 Emx1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Emx1 NCBI NCBI:2016