Enam - enamelin Gene

Also Known as abte

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13801

Summary

A structural constituent of tooth enamel. Acts upstream of or within several processes, including ameloblast differentiation; amelogenesis; and positive regulation of enamel mineralization. Located in extracellular matrix. Is expressed in lower jaw molar; molar enamel organ; and upper jaw incisor. Used to study amelogenesis imperfecta type 1B. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1B and amelogenesis imperfecta type 1C. Orthologous to human ENAM (enamelin). [provided by Alliance of Genome Resources, Apr 2022]

Enam Products (1)

mRNA Protein Name
NM_017468.3 NP_059496.1 enamelin precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables structural constituent of tooth enamel IDA
IDA: Inferred from direct assay
24603688 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within ameloblast differentiation IMP
IMP: Inferred from mutant phenotype
24603688 MGI
acts upstream of or within amelogenesis IMP
IMP: Inferred from mutant phenotype
15649948 MGI
acts upstream of or within odontogenesis of dentin-containing tooth IMP
IMP: Inferred from mutant phenotype
15271968 MGI
acts upstream of or within positive regulation of enamel mineralization IMP
IMP: Inferred from mutant phenotype
24603688 MGI
acts upstream of or within regulation of cell morphogenesis IMP
IMP: Inferred from mutant phenotype
24603688 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular matrix IDA
IDA: Inferred from direct assay
24603688 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

enamelin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04368 ENAM Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19597 Enam Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26093 Enam Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Enam NCBI NCBI:10117