Epb41l2 - erythrocyte membrane protein band 4.1 like 2 Gene
Also Known as 4.1G; NBL2; Epb4.1l2; D10Ertd398e
Species: Mus musculus
Gene Type: protein coding
Gene ID: 13822
Summary
Enables PH domain binding activity and spectrin binding activity. Predicted to be involved in actomyosin structure organization and positive regulation of protein localization to cell cortex. Predicted to act upstream of or within actin Cytoskeleton organization and regulation of cell shape. Predicted to be located in actin cytoskeleton; cell junction; and nucleoplasm. Predicted to be part of COP9 signalosome. Predicted to be active in Cytoskeleton and plasma membrane. Is expressed in several structures, including bone; central nervous system; sensory organ; thymus; and urinary system. Orthologous to human EPB41L2 (erythrocyte membrane protein band 4.1 like 2). [provided by Alliance of Genome Resources, Apr 2022]
Epb41l2 Products (52)
| mRNA | Protein | Name |
|---|---|---|
| NM_001199265.2 | NP_001186194.1 | band 4.1-like protein 2 isoform 1 |
| NM_001358751.2 | NP_001345680.1 | band 4.1-like protein 2 isoform 2 |
| NM_001358753.2 | NP_001345682.1 | band 4.1-like protein 2 isoform 3 |
| NM_001358754.2 | NP_001345683.1 | band 4.1-like protein 2 isoform 4 |
| NM_001358755.2 | NP_001345684.1 | band 4.1-like protein 2 isoform 5 |
| NM_001404797.1 | NP_001391726.1 | band 4.1-like protein 2 isoform 6 |
| NM_001404798.1 | NP_001391727.1 | band 4.1-like protein 2 isoform 7 |
| NM_001404799.1 | NP_001391728.1 | band 4.1-like protein 2 isoform 7 |
| NM_001404801.1 | NP_001391730.1 | band 4.1-like protein 2 isoform 8 |
| NM_001404802.1 | NP_001391731.1 | band 4.1-like protein 2 isoform 9 |
| NM_001404803.1 | NP_001391732.1 | band 4.1-like protein 2 isoform 2 |
| NM_001404805.1 | NP_001391734.1 | band 4.1-like protein 2 isoform 2 |
| NM_001404806.1 | NP_001391735.1 | band 4.1-like protein 2 isoform 2 |
| NM_001404807.1 | NP_001391736.1 | band 4.1-like protein 2 isoform 2 |
| NM_001404808.1 | NP_001391737.1 | band 4.1-like protein 2 isoform 2 |
| NM_001404809.1 | NP_001391738.1 | band 4.1-like protein 2 isoform 2 |
| NM_001404810.1 | NP_001391739.1 | band 4.1-like protein 2 isoform 10 |
| NM_001404811.1 | NP_001391740.1 | band 4.1-like protein 2 isoform 11 |
| NM_001404812.1 | NP_001391741.1 | band 4.1-like protein 2 isoform 12 |
| NM_001404813.1 | NP_001391742.1 | band 4.1-like protein 2 isoform 12 |
| NM_001404815.1 | NP_001391744.1 | band 4.1-like protein 2 isoform 12 |
| NM_001404816.1 | NP_001391745.1 | band 4.1-like protein 2 isoform 13 |
| NM_001404818.1 | NP_001391747.1 | band 4.1-like protein 2 isoform 14 |
| NM_001404819.1 | NP_001391748.1 | band 4.1-like protein 2 isoform 15 |
| NM_001404828.1 | NP_001391757.1 | band 4.1-like protein 2 isoform 15 |
| NM_001404829.1 | NP_001391758.1 | band 4.1-like protein 2 isoform 15 |
| NM_001404830.1 | NP_001391759.1 | band 4.1-like protein 2 isoform 16 |
| NM_001404831.1 | NP_001391760.1 | band 4.1-like protein 2 isoform 16 |
| NM_001404832.1 | NP_001391761.1 | band 4.1-like protein 2 isoform 16 |
| NM_001404833.1 | NP_001391762.1 | band 4.1-like protein 2 isoform 4 |
| NM_001404834.1 | NP_001391763.1 | band 4.1-like protein 2 isoform 4 |
| NM_001404835.1 | NP_001391764.1 | band 4.1-like protein 2 isoform 4 |
| NM_001404837.1 | NP_001391766.1 | band 4.1-like protein 2 isoform 4 |
| NM_001404838.1 | NP_001391767.1 | band 4.1-like protein 2 isoform 4 |
| NM_001404839.1 | NP_001391768.1 | band 4.1-like protein 2 isoform 4 |
| NM_001404840.1 | NP_001391769.1 | band 4.1-like protein 2 isoform 4 |
| NM_001404841.1 | NP_001391770.1 | band 4.1-like protein 2 isoform 17 |
| NM_001404842.1 | NP_001391771.1 | band 4.1-like protein 2 isoform 18 |
| NM_001404843.1 | NP_001391772.1 | band 4.1-like protein 2 isoform 19 |
| NM_001404844.1 | NP_001391773.1 | band 4.1-like protein 2 isoform 19 |
| NM_001404845.1 | NP_001391774.1 | band 4.1-like protein 2 isoform 19 |
| NM_001404846.1 | NP_001391775.1 | band 4.1-like protein 2 isoform 20 |
| NM_001404847.1 | NP_001391776.1 | band 4.1-like protein 2 isoform 5 |
| NM_001404848.1 | NP_001391777.1 | band 4.1-like protein 2 isoform 5 |
| NM_001404849.1 | NP_001391778.1 | band 4.1-like protein 2 isoform 5 |
| NM_001404850.1 | NP_001391779.1 | band 4.1-like protein 2 isoform 5 |
| NM_001404851.1 | NP_001391780.1 | band 4.1-like protein 2 isoform 5 |
| NM_001404852.1 | NP_001391781.1 | band 4.1-like protein 2 isoform 5 |
| NM_001404853.1 | NP_001391782.1 | band 4.1-like protein 2 isoform 5 |
| NM_001404854.1 | NP_001391783.1 | band 4.1-like protein 2 isoform 21 |
| NM_001404855.1 | NP_001391784.1 | band 4.1-like protein 2 isoform 21 |
| NM_013511.4 | NP_038539.2 | band 4.1-like protein 2 isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables PH domain binding |
IDA
IDA: Inferred from direct assay
|
18796539 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
18796539 | MGI |
| enables spectrin binding |
IDA
IDA: Inferred from direct assay
|
18796539 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
band 4.1-like protein 2 |
|
|
Related Agents
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Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS04412 | EPB41L2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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