Epb41l3 - erythrocyte membrane protein band 4.1 like 3 Gene

Also Known as 4.1B; Dal1; NBL3; DAL1P; Epb4.1l3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13823

Summary

Predicted to enable cytoskeletal protein-membrane anchor activity. Predicted to be a structural constituent of Cytoskeleton. Involved in several processes, including nervous system development; paranodal junction maintenance; and protein localization to paranode region of axon. Located in juxtaparanode region of axon; paranode region of axon; and postsynaptic density. Colocalizes with axolemma. Is expressed in several structures, including central nervous system; notochord; paraxial mesenchyme; and retina. Orthologous to human EPB41L3 (erythrocyte membrane protein band 4.1 like 3). [provided by Alliance of Genome Resources, Apr 2022]

Epb41l3 Products (6)

mRNA Protein Name
NM_001355732.1 NP_001342661.1 band 4.1-like protein 3 isoform 2
NM_001355733.1 NP_001342662.1 band 4.1-like protein 3 isoform 3
NM_001355734.1 NP_001342663.1 band 4.1-like protein 3 isoform 4
NM_001355735.1 NP_001342664.1 band 4.1-like protein 3 isoform 5
NM_001355736.1 NP_001342665.1 band 4.1-like protein 3 isoform 1
NM_013813.2 NP_038841.1 band 4.1-like protein 3 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21632923 MGI
Biological Process GO Annotation Evidence References Source
involved in axon development IMP
IMP: Inferred from mutant phenotype
21632923 MGI
involved in myelin maintenance IMP
IMP: Inferred from mutant phenotype
21966409 MGI
involved in neuron projection morphogenesis IMP
IMP: Inferred from mutant phenotype
21966409 MGI
involved in paranodal junction assembly IMP
IMP: Inferred from mutant phenotype
21966409 MGI
involved in paranodal junction maintenance IMP
IMP: Inferred from mutant phenotype
21632923 MGI
involved in protein localization to juxtaparanode region of axon IMP
IMP: Inferred from mutant phenotype
21632923 MGI
involved in protein localization to paranode region of axon IMP
IMP: Inferred from mutant phenotype
21632923 MGI
involved in protein localization to plasma membrane IMP
IMP: Inferred from mutant phenotype
21966409 MGI
involved in regulation of cell shape IMP
IMP: Inferred from mutant phenotype
21966409 MGI
Cellular Component GO Annotation Evidence References Source
colocalizes with axolemma IDA
IDA: Inferred from direct assay
21966409 MGI
located in juxtaparanode region of axon IDA
IDA: Inferred from direct assay
12975355 MGI
located in paranode region of axon IDA
IDA: Inferred from direct assay
12975355 MGI
located in postsynaptic density IDA
IDA: Inferred from direct assay
17114649 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

band 4.1-like protein 3

  • DAL-1

  • differentially expressed in adenocarcinoma of the lung protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04413 EPB41L3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Epb41l3 NCBI NCBI:23136