Esx1 - extraembryonic, spermatogenesis, homeobox 1 Gene

Also Known as Spx1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13984

Summary

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within labyrinthine layer blood vessel development; labyrinthine layer morphogenesis; and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including central nervous system; extraembryonic component; genitourinary system; hindlimb phalanx; and viscerocranium. Orthologous to human ESX1 (ESX homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Esx1 Products (1)

mRNA Protein Name
NM_007957.2 NP_031983.2 homeobox protein ESX1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within blood vessel development IMP
IMP: Inferred from mutant phenotype
9806555 MGI
acts upstream of or within labyrinthine layer blood vessel development IMP
IMP: Inferred from mutant phenotype
9806555 MGI
acts upstream of or within labyrinthine layer morphogenesis IMP
IMP: Inferred from mutant phenotype
9806555 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
19796622 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
19796622 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein ESX1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04547 ESX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Esx1 NCBI NCBI:80712