2. Gene
  3. Smarcad1 - SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 Gene

Smarcad1 - SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Etl1; etl-1; D6Pas1; mKIAA1122

Gene ID: 13990 | Gene type: protein coding

About Smarcad1

Summary

Predicted to enable ATP-dependent activity, acting on DNA; DNA binding activity; and chromatin binding activity. Predicted to be involved in several processes, including DNA double-strand break processing; chromosome separation; and histone deacetylation. Predicted to act upstream of or within DNA repair and chromatin organization. Located in heterochromatin and nucleus. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and integumental system. Used to study asphyxiating thoracic dystrophy. Human ortholog(s) of this gene implicated in BASAN syndrome and adermatoglyphia. Orthologous to human SMARCAD1 (SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1). [provided by Alliance of Genome Resources, Apr 2022]

Smarcad1 Products(7)

mRNA Protein Name
NM_001253392.1 NP_001240321.1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 isoform 2
NM_001355248.2 NP_001342177.1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 isoform 3
NM_001355249.2 NP_001342178.1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 isoform 3
NM_001355250.2 NP_001342179.1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 isoform 1
NM_001409790.1 NP_001396719.1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 isoform 2
NM_001409791.1 NP_001396720.1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 isoform 3
NM_007958.3 NP_031984.1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 isoform 1
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in heterochromatin IDA
IDA: Inferred from direct assay
21549307 MGI
located in nucleus IDA
IDA: Inferred from direct assay
8219362 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

ATP-dependent helicase SMARCAD1

enhancer trap locus 1

enhancer trap locus homolog 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13407 SMARCAD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smarcad1 NCBI NCBI:56916