ASB5 - ankyrin repeat and SOCS box containing 5 Gene

Also Known as ASB-5

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 140458

About ASB5

Cytogenetic location: 4q34.2 Genomic coordinates (GRCh38): 4:176,213,673-176,277,524 (from NCBI)

This gene has 6 transcripts (splice variants), 136 orthologues and 2 paralogues. Biased expression in prostate (RPKM 5.3), urinary bladder (RPKM 4.0) and 6 other tissues.

Summary

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known. [provided by RefSeq, Jul 2008]

ASB5 Products (2)

mRNA Protein Name
NM_001410863.1 NP_001397792.1 ankyrin repeat and SOCS box protein 5 isoform 2
NM_080874.4 NP_543150.1 ankyrin repeat and SOCS box protein 5 isoform 1

ASB5 Protein Structure

Ank_2

Ank_2: Ankyrin repeats (3 copies) (74 - 164)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (173 - 263)

SOCS_box

SOCS_box: SOCS box (290 - 329)

  • 0
  • 100
  • 200
  • 300
  • 329 a.a.
Protein Preferred Names Protein Names

ankyrin repeat and SOCS box protein 5

  • SOCS box protein ASB-5

ASB5 Antibodies

Cat. No. Product Name Application Reactivity
HY-P89722 ASB-5 Antibody (YA9066) WB, ICC/IF, IF-Tissue, IP, ELISA human

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01070 ASB5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus ASB5 VGNC VGNC:59961
Rattus norvegicus ASB5 RGD RGD:1565973
Canis familiaris ASB5 VGNC VGNC:38165
Bos taurus ASB5 VGNC VGNC:26198
Mus musculus ASB5 MGD MGI:1923544
Macaca mulatta ASB5 VGNC VGNC:69849
Others ASB5 NCBI