ASB8 - ankyrin repeat and SOCS box containing 8 Gene

Also Known as PP14212

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 140461

About ASB8

Cytogenetic location: 12q13.11 Genomic coordinates (GRCh38): 12:48,147,789-48,157,515 (from NCBI)

This gene has 18 transcripts (splice variants) and 193 orthologues. Ubiquitous expression in heart (RPKM 11.8), kidney (RPKM 11.3) and 25 other tissues.

Summary

Predicted to be involved in intracellular signal transduction and protein ubiquitination. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

ASB8 Products (7)

mRNA Protein Name
NM_001319296.2 NP_001306225.1 ankyrin repeat and SOCS box protein 8 isoform a
NM_001319297.2 NP_001306226.1 ankyrin repeat and SOCS box protein 8 isoform a
NM_001319298.2 NP_001306227.1 ankyrin repeat and SOCS box protein 8 isoform b
NM_001319299.2 NP_001306228.1 ankyrin repeat and SOCS box protein 8 isoform b
NM_001319300.2 NP_001306229.1 ankyrin repeat and SOCS box protein 8 isoform c
NM_001319301.2 NP_001306230.1 ankyrin repeat and SOCS box protein 8 isoform c
NM_024095.5 NP_077000.1 ankyrin repeat and SOCS box protein 8 isoform a

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32814053 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ASB8 Protein Structure

Ank_5

Ank_5: Ankyrin repeats (many copies) (40 - 93)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (96 - 178)

SOCS_box

SOCS_box: SOCS box (247 - 286)

  • 0
  • 100
  • 200
  • 288 a.a.
Protein Preferred Names Protein Names

ankyrin repeat and SOCS box protein 8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01073 ASB8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ASB8 VGNC VGNC:69852
Mus musculus ASB8 MGD MGI:1925791
Rattus norvegicus ASB8 RGD RGD:1309246
Canis familiaris ASB8 VGNC VGNC:38168
Felis catus ASB8 VGNC VGNC:59964
Bos taurus ASB8 VGNC VGNC:26201