Bsnd - barttin CLCNK type accessory beta subunit Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 140475

Summary

Contributes to Chloride Channel activity. Predicted to be involved in chloride transport. Predicted to act upstream of or within cellular ion homeostasis. Located in basolateral plasma membrane. Is integral component of plasma membrane. Part of protein-containing complex. Is expressed in central nervous system; inner ear; and metanephros. Used to study Bartter disease type 4a. Human ortholog(s) of this gene implicated in Bartter disease; Bartter disease type 4a; and sensorineural hearing loss. Orthologous to human BSND (barttin CLCNK type accessory subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Bsnd Products (1)

mRNA Protein Name
NM_080458.2 NP_536706.2 barttin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
contributes to chloride channel activity IDA
IDA: Inferred from direct assay
11734858 MGI
enables chloride channel regulator activity IDA
IDA: Inferred from direct assay
23791703 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11734858 MGI
Biological Process GO Annotation Evidence References Source
involved in sensory perception of sound IMP
IMP: Inferred from mutant phenotype
18833191 MGI
Cellular Component GO Annotation Evidence References Source
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
11734858 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
11734858 MGI
part of protein-containing complex IDA
IDA: Inferred from direct assay
11734858 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

barttin

  • Bartter syndrome, infantile, with sensorineural deafness (Barttin)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01645 BSND Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bsnd NCBI NCBI:7809