Pcyt1a - phosphate cytidylyltransferase 1A, choline Gene

Also Known as CTP; CCT-alpha

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 140544

Summary

Enables several functions, including Calmodulin binding activity; choline-phosphate cytidylyltransferase activity; and phosphatidylcholine binding activity. Involved in CDP-choline pathway. Located in endoplasmic reticulum; nuclear envelope; and plasma membrane. Human ortholog(s) of this gene implicated in spondylometaphyseal dysplasia with cone-rod dystrophy. Orthologous to human PCYT1A (phosphate cytidylyltransferase 1A, choline). [provided by Alliance of Genome Resources, Apr 2022]

Pcyt1a Products (1)

mRNA Protein Name
NM_078622.2 NP_511177.2 choline-phosphate cytidylyltransferase A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables calmodulin binding IDA
IDA: Inferred from direct assay
17804406 RGD
enables choline-phosphate cytidylyltransferase activity IDA
IDA: Inferred from direct assay
2166941 RGD
enables choline-phosphate cytidylyltransferase activity IMP
IMP: Inferred from mutant phenotype
7654214 RGD
enables lipid binding EXP
EXP: Inferred from Experiment
14529288 RGD
enables lipid binding IMP
IMP: Inferred from mutant phenotype
2166941 RGD
enables molecular function inhibitor activity IDA
IDA: Inferred from direct assay
24275660 RGD
enables phosphatidylcholine binding IDA
IDA: Inferred from direct assay
9224626 RGD
enables protein homodimerization activity IPI
IPI: Inferred from physical interaction
19783652 RGD
Biological Process GO Annotation Evidence Verweise Source
involved in CDP-choline pathway IDA
IDA: Inferred from direct assay
8185307 RGD
involved in phosphatidylcholine biosynthetic process IDA
IDA: Inferred from direct assay
8185307 RGD
involved in phosphatidylcholine biosynthetic process IMP
IMP: Inferred from mutant phenotype
12718547 RGD
Cellular Component GO Annotation Evidence Verweise Source
located in nuclear envelope IDA
IDA: Inferred from direct assay
11583989 RGD
located in nucleus IDA
IDA: Inferred from direct assay
8185307 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

choline-phosphate cytidylyltransferase A

  • CCT A

  • CT A

  • CTP:phosphocholine cytidylyl transferase

  • CTP:phosphocholine cytidylyltransferase A

  • CTP:phosphocholine cytidylyltransferase alpha

  • choline phosphate cytidylyltransferase 1 alpha

  • choline-phosphate cytidylyltransferase A-like

  • phosphate cytid

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS10180 PCYT1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pcyt1a NCBI NCBI:5130