2. Gene
  3. Smc1b - structural maintenance of chromosomes 1B Gene

Smc1b - structural maintenance of chromosomes 1B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as SMC-1B; Smc1l2; SMC1beta

Gene ID: 140557 | Gene type: protein coding

About Smc1b

Summary

Enables DNA binding activity. Acts upstream of or within meiotic cell cycle and sister chromatid cohesion. Located in chromosome, centromeric region and lateral element. Part of nuclear meiotic cohesin complex. Orthologous to human SMC1B (structural maintenance of chromosomes 1B). [provided by Alliance of Genome Resources, Apr 2022]

Smc1b Products(1)

mRNA Protein Name
NM_080470.1 NP_536718.1 structural maintenance of chromosomes protein 1B
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA binding IDA
IDA: Inferred from direct assay
11564881 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11564881 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within meiotic cell cycle IPI
IPI: Inferred from physical interaction
12759374 MGI
acts upstream of or within sister chromatid cohesion IDA
IDA: Inferred from direct assay
11564881 MGI
Cellular Component GO Annotation Evidence Reference Source
located in chromosome, centromeric region IDA
IDA: Inferred from direct assay
11564881 MGI
located in condensed nuclear chromosome IDA
IDA: Inferred from direct assay
22164254 MGI
located in lateral element IDA
IDA: Inferred from direct assay
15870106 MGI
part of meiotic cohesin complex IDA
IDA: Inferred from direct assay
21527826 MGI
located in synaptonemal complex IDA
IDA: Inferred from direct assay
11564881 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

structural maintenance of chromosomes protein 1B

SMC protein 1B

SMC-1-beta

structural maintenace of chromosomes 1B

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13417 SMC1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smc1b NCBI NCBI:27127