SOGA1 - suppressor of glucose, autophagy associated 1 Gene

Also Known as SOGA; KIAA0889; C20orf117

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 140710

About SOGA1

This gene has 4 transcripts (splice variants), 267 orthologues and 2 paralogues. Ubiquitous expression in thyroid (RPKM 9.7), brain (RPKM 6.2) and 22 other tissues.

Summary

Predicted to be involved in Insulin Receptor signaling pathway; negative regulation of gluconeogenesis; and regulation of Autophagy. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

SOGA1 Products (2)

mRNA Protein Name
NM_080627.4 NP_542194.2 protein SOGA1 isoform 1
NM_199181.3 NP_954650.2 protein SOGA1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence References Source
involved in chromosome segregation IMP
IMP: Inferred from mutant phenotype
33587225 GOA
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
20813965 GOA
located in microtubule IDA
IDA: Inferred from direct assay
33587225 GOA
located in midbody IDA
IDA: Inferred from direct assay
33587225 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SOGA1 Protein Structure

SOGA

SOGA: Protein SOGA (379 - 474)

SOGA

SOGA: Protein SOGA (507 - 598)

DUF4482

DUF4482: Domain of unknown function (DUF4482) (1069 - 1209)

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  • 1661 a.a.
Protein Preferred Names Protein Names

protein SOGA1

  • SOGA family member 1

Related Diseases

Diseases Alias
Enterokinase Deficiency

  • Enteropeptidase Deficiency

  • Congenital Enterokinase Deficiency

  • Congenital Enteropathy Due To Enteropeptidase Deficiency

  • Deficiency Of Enteropeptidase

  • ENTKD
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13562 SOGA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris SOGA1 VGNC VGNC:46655
Bos taurus SOGA1 VGNC VGNC:35127
Felis catus SOGA1 VGNC VGNC:65567
Macaca mulatta SOGA1 VGNC VGNC:77715
Mus musculus SOGA1 MGD MGI:2444575
Rattus norvegicus SOGA1 RGD RGD:1563627
Others SOGA1 NCBI