NANP - N-acetylneuraminic acid phosphatase Gene

Also Known as HDHD4; C20orf147; dJ694B14.3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 140838

About NANP

Cytogenetic location: 20p11.21 Genomic coordinates (GRCh38): 20:25,612,935-25,624,014 (from NCBI)

This gene has 1 transcript (splice variant), 213 orthologues and 1 paralogue. Ubiquitous expression in adrenal (RPKM 2.0), testis (RPKM 1.9) and 25 other tissues.

Summary

Enables N-acylneuraminate-9-phosphatase activity. Involved in N-acetylneuraminate biosynthetic process. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

NANP Products (1)

mRNA Protein Name
NM_152667.3 NP_689880.1 N-acylneuraminate-9-phosphatase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables N-acylneuraminate-9-phosphatase activity IDA
IDA: Inferred from direct assay
16237198 GOA
Biological Process GO Annotation Evidence References Source
involved in CMP-N-acetylneuraminate biosynthetic process IMP
IMP: Inferred from mutant phenotype
31121216 GOA
involved in N-acetylneuraminate biosynthetic process IDA
IDA: Inferred from direct assay
16237198 GOA
involved in glycosylation IMP
IMP: Inferred from mutant phenotype
31121216 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NANP Protein Structure

HAD_2

HAD_2: Haloacid dehalogenase-like hydrolase (9 - 209)

  • 0
  • 100
  • 200
  • 248 a.a.
Protein Preferred Names Protein Names

N-acylneuraminate-9-phosphatase

  • Neu5Ac-9-Pase

Related Diseases

Diseases Alias
Balanoposthitis

  • Balanitis Due To Infection
Intracranial Abscess

  • Abscess Of Brain

  • Brain Empyema

  • Cranial Abscess

  • Intracerebral Abscess

  • Cerebral Abscess

  • Cerebral Embolic Abscess

  • Cerebral Pyogenic Abscess

  • Septic Brain Infection

  • Temporosphenoidal Abscess

  • Ventricular Empyema

  • Intracranial Suppuration

  • Intracranial Vein Sinus Abscess
Benign Essential Hypertension
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P11473 NANP6 peptide / Unkown
HY-RS09024 NANP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus NANP MGD MGI:1914561
Bos taurus NANP VGNC VGNC:31877
Macaca mulatta NANP VGNC VGNC:74971
Rattus norvegicus NANP RGD RGD:1306009
Others NANP NCBI