Psmc3ip - PSMC3 interacting protein Gene

Rattus norvegicus

Also known as Gt198; Tbpip

Gene ID: 140938 | Gene type: protein coding

About Psmc3ip

Summary

Enables DNA binding domain binding activity; nuclear receptor binding activity; and nuclear receptor coactivator activity. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleus. Human ortholog(s) of this gene implicated in ovarian dysgenesis 3. Orthologous to human PSMC3IP (PSMC3 interacting protein). [provided by Alliance of Genome Resources, Apr 2022]

Psmc3ip Products(1)

mRNA	Protein	Name
NM_134458.2	NP_604453.2	homologous-pairing protein 2 homolog

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA binding domain binding	IDA IDA: Inferred from direct assay	11739747	RGD
enables nuclear androgen receptor binding	IDA IDA: Inferred from direct assay	11739747	RGD
enables nuclear estrogen receptor binding	IDA IDA: Inferred from direct assay	11739747	RGD
enables nuclear glucocorticoid receptor binding	IDA IDA: Inferred from direct assay	11739747	RGD
enables nuclear receptor coactivator activity	IDA IDA: Inferred from direct assay	11739747	RGD
enables nuclear thyroid hormone receptor binding	IDA IDA: Inferred from direct assay	11739747	RGD
enables protein-containing complex binding	IMP IMP: Inferred from mutant phenotype	11739747	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	11739747	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

homologous-pairing protein 2 homolog

nuclear receptor coactivator GT198	proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein
proteasome 26S ATPase subunit 3-interacting protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11313	PSMC3IP Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Psmc3ip	NCBI	NCBI:29893

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