2. Gene
  3. Foxi1 - forkhead box I1 Gene

Foxi1 - forkhead box I1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Hfh3; Fkh10; HFH-3; FREAC6; 5830401E05Rik

Gene ID: 14233 | Gene type: protein coding

About Foxi1

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription, DNA-templated. Acts upstream of or within inner ear morphogenesis and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleolus. Is expressed in several structures, including alimentary system; metanephros; nervous system; sensory organ; and skeleton. Used to study Pendred Syndrome. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 4. Orthologous to human FOXI1 (forkhead box I1). [provided by Alliance of Genome Resources, Apr 2022]

Foxi1 Products(1)

mRNA Protein Name
NM_023907.4 NP_076396.3 forkhead box protein I1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
16159312 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
16159312 MGI
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
16159312 MGI
enables transcription cis-regulatory region binding IDA
IDA: Inferred from direct assay
7958446 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within inner ear morphogenesis IMP
IMP: Inferred from mutant phenotype
12642503 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
16159312 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
7958446 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
16159312 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

forkhead box protein I1

HNF-3/forkhead homolog 3

forkhead homolog 10

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05053 FOXI1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Foxi1 NCBI NCBI:2299