Foxs1 - forkhead box S1 Gene

Also Known as Fkh3; Fkhl18; FREAC10

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14239

Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in blood vessel development; negative regulation of DNA-binding transcription factor activity; and negative regulation of transcription by RNA polymerase II. Acts upstream of or within neuromuscular process controlling balance and regulation of growth. Located in nucleus. Is expressed in several structures, including cardiovascular system; ganglia; genitourinary system; hemolymphoid system gland; and yolk sac. Orthologous to human FOXS1 (forkhead box S1). [provided by Alliance of Genome Resources, Apr 2022]

Foxs1 Products (1)

mRNA Protein Name
NM_010226.2 NP_034356.1 forkhead box protein S1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
18288644 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
18288644 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
18288644 MGI
Biological Process GO Annotation Evidence References Source
involved in blood vessel development IMP
IMP: Inferred from mutant phenotype
18288644 MGI
involved in negative regulation of DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
18288644 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
18288644 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
18288644 MGI
acts upstream of or within neuromuscular process controlling balance IMP
IMP: Inferred from mutant phenotype
15964817 MGI
acts upstream of or within positive regulation of multicellular organism growth IMP
IMP: Inferred from mutant phenotype
15964817 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
18288644 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

forkhead box protein S1

  • FREAC-10

  • forkhead-like 18 protein

  • forkhead-related transcription factor 10

  • transcription factor FKH-3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05082 FOXS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Foxs1 NCBI NCBI:2307