2. Gene
  3. Fmn1 - formin 1 Gene

Fmn1 - formin 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as ld; Fmn; formin-1

Gene ID: 14260 | Gene type: protein coding

About Fmn1

Summary

Enables SH3 domain binding activity and microtubule binding activity. Acts upstream of or within several processes, including animal organ morphogenesis; limb morphogenesis; and positive regulation of cellular component organization. Located in cytoplasm; microtubule cytoskeleton; and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb bud; and spleen. Orthologous to human FMN1 (formin 1). [provided by Alliance of Genome Resources, Apr 2022]

Fmn1 Products(5)

mRNA Protein Name
NM_001285458.1 NP_001272387.1 formin-1 isoform 3
NM_001285459.1 NP_001272388.1 formin-1 isoform 4
NM_001287817.1 NP_001274746.1 formin-1 isoform 5
NM_001287818.1 NP_001274747.1 formin-1 isoform 5
NM_010230.2 NP_034360.2 formin-1 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables SH3 domain binding IPI
IPI: Inferred from physical interaction
8438166 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
8605874 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within forelimb morphogenesis IMP
IMP: Inferred from mutant phenotype
17554679 MGI
acts upstream of or within gene expression IMP
IMP: Inferred from mutant phenotype
17554679 MGI
acts upstream of or within hindlimb morphogenesis IMP
IMP: Inferred from mutant phenotype
17554679 MGI
acts upstream of or within limb development IMP
IMP: Inferred from mutant phenotype
2997621 MGI
acts upstream of or within positive regulation of actin filament polymerization IDA
IDA: Inferred from direct assay
14647292 MGI
acts upstream of or within positive regulation of actin nucleation IDA
IDA: Inferred from direct assay
14647292 MGI
acts upstream of or within positive regulation of focal adhesion assembly IMP
IMP: Inferred from mutant phenotype
18560567 MGI
acts upstream of or within skeletal system morphogenesis IMP
IMP: Inferred from mutant phenotype
17554679 MGI
acts upstream of or within ureteric bud invasion IMP
IMP: Inferred from mutant phenotype
7517224 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
8798555 MGI
located in nucleus IDA
IDA: Inferred from direct assay
8798555 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

formin-1

limb deformity protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05000 FMN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W141871 DL-Thyronine / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fmn1 NCBI NCBI:342184