Slc34a3 - solute carrier family 34 (sodium phosphate), member 3 Gene

Also Known as Npt2c; NptIIc; naPi-2c; Npt2c-v1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 142681

Summary

Enables sodium:phosphate symporter activity. Acts upstream of or within phosphate ion transport. Located in apical plasma membrane and brush border. Is expressed in several structures, including extraembryonic component; genitourinary system; and small intestine. Human ortholog(s) of this gene implicated in hereditary hypophosphatemic rickets with hypercalciuria. Orthologous to human SLC34A3 (solute carrier family 34 member 3). [provided by Alliance of Genome Resources, Apr 2022]

Slc34a3 Products (2)

mRNA Protein Name
NM_001362748.1 NP_001349677.1 sodium-dependent phosphate transport protein 2C isoform 2
NM_080854.3 NP_543130.2 sodium-dependent phosphate transport protein 2C isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables sodium:phosphate symporter activity IDA
IDA: Inferred from direct assay
12690469 MGI
enables sodium:phosphate symporter activity IMP
IMP: Inferred from mutant phenotype
16113079 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within phosphate ion transport IDA
IDA: Inferred from direct assay
12690469 MGI
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
12690469 MGI
located in brush border IDA
IDA: Inferred from direct assay
12690469 MGI
located in brush border membrane IDA
IDA: Inferred from direct assay
12690469 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium-dependent phosphate transport protein 2C

  • Na(+)-dependent phosphate cotransporter 2C

  • Na(+)/Pi cotransporter 2C

  • sodium-phosphate cotransporter IIC

  • sodium/phosphate cotransporter 2C

  • type IIc Na+/Pi-cotransporter

  • type IIc NaPi-cotransporter-v1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13194 SLC34A3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc34a3 NCBI NCBI:142680