Slc34a3 - solute carrier family 34 (sodium phosphate), member 3 Gene

Mus musculus

Also known as Npt2c; NptIIc; naPi-2c; Npt2c-v1

Gene ID: 142681 | Gene type: protein coding

About Slc34a3

Summary

Enables sodium:phosphate symporter activity. Acts upstream of or within phosphate ion transport. Located in apical plasma membrane and brush border. Is expressed in several structures, including extraembryonic component; genitourinary system; and small intestine. Human ortholog(s) of this gene implicated in hereditary hypophosphatemic rickets with hypercalciuria. Orthologous to human SLC34A3 (solute carrier family 34 member 3). [provided by Alliance of Genome Resources, Apr 2022]

Slc34a3 Products(2)

mRNA	Protein	Name
NM_001362748.1	NP_001349677.1	sodium-dependent phosphate transport protein 2C isoform 2
NM_080854.3	NP_543130.2	sodium-dependent phosphate transport protein 2C isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables sodium:phosphate symporter activity	IDA IDA: Inferred from direct assay	12690469	MGI
enables sodium:phosphate symporter activity	IMP IMP: Inferred from mutant phenotype	16113079	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within phosphate ion transport	IDA IDA: Inferred from direct assay	12690469	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in apical plasma membrane	IDA IDA: Inferred from direct assay	12690469	MGI
located in brush border	IDA IDA: Inferred from direct assay	12690469	MGI
located in brush border membrane	IDA IDA: Inferred from direct assay	12690469	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

sodium-dependent phosphate transport protein 2C

Na(+)-dependent phosphate cotransporter 2C	Na(+)/Pi cotransporter 2C
sodium-phosphate cotransporter IIC	sodium/phosphate cotransporter 2C
type IIc Na+/Pi-cotransporter	type IIc NaPi-cotransporter-v1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13194	SLC34A3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc34a3	NCBI	NCBI:142680

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