LIPJ - lipase family member J Gene

Homo sapiens

Also known as LIPL1; bA425M17.2

Gene ID: 142910 | Gene type: protein coding

About LIPJ

Cytogenetic location: 10q23.31 Genomic coordinates (GRCh38): 10:88,582,907-88,623,184 (from NCBI)

This gene has 3 transcripts (splice variants), 114 orthologues and 5 paralogues. Broad expression in testis (RPKM 1.7), thyroid (RPKM 0.3) and 20 other tissues.

Summary

Predicted to enable hydrolase activity, acting on ester bonds. Predicted to be involved in lipid catabolic process. Predicted to be active in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]

LIPJ Products(2)

mRNA	Protein	Name
NM_001010939.3	NP_001010939.2	lipase member J isoform 1
NM_001394640.1	NP_001381569.1	lipase member J isoform 2

LIPJ Protein Structure

Abhydro_lipase

Abhydrolase_1

0
100
200
300
366 a.a.

Protein Preferred Names

Protein Names

lipase member J

lipase J

Related Diseases

Diseases

Alias

Lysosomal And Lipase Deficiency

Cerebrooculofacioskeletal Syndrome 4

COFS4	Cerebro-Oculo-Facio-Skeletal Syndrome 4
Cofs Syndrome	Cerebrooculofacioskeletal Syndrome, Type 4

Mixed Sleep Apnea

Complex Sleep Apnea

Sleep Apnea, Mixed Central And Obstructive

Lysosomal Acid Lipase Deficiency

Wolman Disease	Cholesteryl Ester Storage Disease
Lal Deficiency	Lipa Deficiency
Cholesterol Ester Storage Disease	CESD
Cholesterol Ester Hydrolase Deficiency	Acid Lipase Deficiency
Acid Esterase Deficiency	Familial Xanthomatosis
Wolman Xanthomatosis	Wolman'S Disease
Wolman'S Or Triglyceride Storage Type Iii Disease	Xanthomatosis, Familial
Liposomal Acid Lipase Deficiency, Wolman Type	Familial Visceral Xanthomatosis
Primary Familial Xanthomatosis	Primary Familial Xanthomatosis With Adrenal Calcification
Acid Lipase Disease	WOD
Acid Cholesteryl Ester Hydrolase Deficiency, Type 2

Fusariosis

Fusarium Infection

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07692	LIPJ Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	LIPJ	VGNC	VGNC:30906
Macaca mulatta	LIPJ	VGNC	VGNC:74333
Canis familiaris	LIPJ	VGNC	VGNC:42699
Felis catus	LIPJ	VGNC	VGNC:63241
Rattus norvegicus	LIPJ	RGD	RGD:2321667