Ganab - alpha glucosidase 2 alpha neutral subunit Gene

Mus musculus

Also known as G2an; GluII; mKIAA0088

Gene ID: 14376 | Gene type: protein coding

About Ganab

Summary

Enables glucan 1,3-alpha-glucosidase activity. Involved in N-glycan processing. Part of glucosidase II complex. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in polycystic kidney disease; polycystic kidney disease 3; and polycystic liver disease. Orthologous to human GANAB (glucosidase II alpha subunit). [provided by Alliance of Genome Resources, Apr 2022]

Ganab Products(3)

mRNA	Protein	Name
NM_001293621.2	NP_001280550.1	neutral alpha-glucosidase AB isoform 2 precursor
NM_001410311.1	NP_001397240.1	neutral alpha-glucosidase AB isoform 3
NM_008060.3	NP_032086.1	neutral alpha-glucosidase AB isoform 1

Protein Preferred Names

Protein Names

neutral alpha-glucosidase AB

alpha-glucosidase 2	carbohydrate processing enzyme of the endoplasmic reticulum
glucosidase II alpha-subunit	glucosidase II subunit alpha

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-178202	5-C-phenethyl-DNJ	Inhibitor	/	Unkown
HY-RS05270	GANAB Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ganab	NCBI	NCBI:23193

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