TTC36 - tetratricopeptide repeat domain 36 Gene

Also Known as HBP21

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 143941

About TTC36

This gene has 3 transcripts (splice variants) and 188 orthologues. Biased expression in liver (RPKM 51.1), kidney (RPKM 9.2) and 2 other tissues.

Summary

The protein encoded by this gene has three tetratricopeptide repeats and is a chaperone for heat shock protein 70. The encoded protein may function as a tumor suppressor in hepatocellular carcinoma (HCC) since it promotes Apoptosis but is downregulated in HCC. [provided by RefSeq, Sep 2016]

TTC36 Products (4)

mRNA Protein Name
NM_001080441.4 NP_001073910.1 tetratricopeptide repeat protein 36 isoform a
NM_001346096.2 NP_001333025.1 tetratricopeptide repeat protein 36 isoform b
NM_001346097.2 NP_001333026.1 tetratricopeptide repeat protein 36 isoform b
NM_001346098.2 NP_001333027.1 tetratricopeptide repeat protein 36 isoform c

TTC36 Protein Structure

TPR_11

TPR_11: TPR repeat (50 - 115)

TPR_2

TPR_2: Tetratricopeptide repeat (128 - 152)

  • 0
  • 100
  • 189 a.a.
Protein Preferred Names Protein Names

tetratricopeptide repeat protein 36

  • HSP70 binding protein 21

Related Diseases

Diseases Alias
Tyrosinemia, Type Iii

  • Tyrosinemia Type Iii

  • 4-Hydroxyphenylpyruvate Dioxygenase Deficiency

  • TYRSN3

  • 4-Hydroxyphenylpyruvic Acid Oxidase Deficiency

  • Tyrosinemia Type 3

  • 4-Alpha Hydroxyphenylpyruvate Dioxygenase Deficiency

  • 4-Alpha Hydroxyphenylpyruvic Acid Oxidase Deficiency

  • Tyrosinemia Due To 4-Hydroxyphenylpyruvate Dioxygenase Deficiency

  • Tyrosinemia Due To 4-Hydroxyphenylpyruvic Acid Oxidase Deficiency

  • Tyrosinemia Due To Hpd Deficiency

  • Tyrosinemia 3
Hepatocellular Carcinoma

  • Liver Cancer

  • Primary Liver Cancer

  • HCC

  • Hepatoma

  • Malignant Neoplasm Of Liver

  • Liver Neoplasms

  • Cancer, Hepatocellular

  • Liver Cell Carcinoma

  • Lcc

  • Hepatoblastoma, Somatic

  • Hepatic Cancer

  • Primary Malignant Neoplasm Of Liver

  • Rare Tumor Of Liver And Intrahepatic Biliary Tract

  • Hepatocellular Carcinoma, Somatic

  • Hepatocellular Carcinoma, Childhood Type, Somatic

  • Hepatocellular Cancer, Somatic

  • Ca Liver - Primary

  • Hepatic Neoplasm

  • Malignant Hepato-Biliary Neoplasm

  • Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

  • Malignant Neoplasm Of Liver, Primary

  • Malignant Tumor Of Liver

  • Neoplasm Of Liver

  • Non-Resectable Primary Hepatic Malignant Neoplasm

  • Resectable Malignant Neoplasm Of Liver

  • Resectable Malignant Neoplasm Of The Liver

  • Primary Liver Carcinoma

  • Primary Malignant Liver Neoplasm

  • Primary Cancer Of Liver

  • Primary Tumor Of The Liver

  • Rare Tumor Of Liver And Ibt

  • Hepatocellular Cancer

  • Neoplasm Of The Liver

  • Carcinoma, Hepatocellular

  • Hepatomas

  • Liver Neoplasm

  • Liver Carcinoma

  • Liver And Intrahepatic Biliary Tract Carcinoma

  • Malignant Hepatobiliary Neoplasm

  • Adult Primary Hepatocellular Carcinoma

  • Hepatoblastoma

  • Carcinoma Of Liver

  • Malignant Liver Tumour

  • Malignant Hepatic Tumour
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15211 TTC36 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris TTC36 VGNC VGNC:47954
Mus musculus TTC36 MGD MGI:2384760
Bos taurus TTC36 VGNC VGNC:36472
Macaca mulatta TTC36 VGNC VGNC:107660
Rattus norvegicus TTC36 RGD RGD:1359544
Felis catus TTC36 VGNC VGNC:81098
Others TTC36 NCBI