Gabra6 - gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6 Gene

Also Known as alpha6; Gabra-6; GABA-ARalpha6

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14399

Summary

Enables transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in several processes, including GABAergic synaptic transmission; chloride transmembrane transport; and gamma-aminobutyric acid signaling pathway. Predicted to act upstream of or within chloride transport. Is active in cerebellar Golgi cell to granule cell synapse. Is expressed in central nervous system and retina. Orthologous to human GABRA6 (gamma-aminobutyric acid type A receptor subunit alpha6). [provided by Alliance of Genome Resources, Apr 2022]

Gabra6 Products (3)

mRNA Protein Name
NM_001099641.2 NP_001093111.1 gamma-aminobutyric acid receptor subunit alpha-6 isoform 1 precursor
NM_001359049.1 NP_001345978.1 gamma-aminobutyric acid receptor subunit alpha-6 isoform 3
NM_008068.3 NP_032094.2 gamma-aminobutyric acid receptor subunit alpha-6 isoform 2 precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential EXP
EXP: Inferred from Experiment
26134650 MGI
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IDA
IDA: Inferred from direct assay
26134650 MGI
Cellular Component GO Annotation Evidence References Source
is active in cerebellar Golgi cell to granule cell synapse EXP
EXP: Inferred from Experiment
26134650 MGI
is active in cerebellar Golgi cell to granule cell synapse IDA
IDA: Inferred from direct assay
26134650 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gamma-aminobutyric acid receptor subunit alpha-6

  • GABA(A) receptor subunit alpha-6

  • GABAA receptor alpha 6 subunit

  • subunit alpha 6 gamma-aminobutyric acid (GABA-A) receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05214 GABRA6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gabra6 NCBI NCBI:2559