Gabrr2 - gamma-aminobutyric acid (GABA) C receptor, subunit rho 2 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14409

Summary

Enables GABA-A receptor activity. Acts upstream of or within gamma-aminobutyric acid signaling pathway and visual perception. Predicted to be located in axon. Predicted to be part of GABA-A receptor complex. Predicted to be active in neuron projection and synapse. Predicted to be integral component of plasma membrane. Is expressed in central nervous system; gut; male reproductive gland or organ; and retina. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human GABRR2 (gamma-aminobutyric acid type A receptor subunit rho2). [provided by Alliance of Genome Resources, Apr 2022]

Gabrr2 Products (1)

mRNA Protein Name
NM_008076.3 NP_032102.2 gamma-aminobutyric acid receptor subunit rho-2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GABA-A receptor activity IMP
IMP: Inferred from mutant phenotype
12019334 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
30902970 MGI
Biological Process GO Annotation Evidence References Source
NOT acts upstream of or within eye photoreceptor cell development IMP
IMP: Inferred from mutant phenotype
12019334 MGI
acts upstream of or within gamma-aminobutyric acid signaling pathway IMP
IMP: Inferred from mutant phenotype
12019334 MGI
acts upstream of or within visual perception IMP
IMP: Inferred from mutant phenotype
12019334 MGI
Cellular Component GO Annotation Evidence References Source
is active in intracellular vesicle IDA
IDA: Inferred from direct assay
30902970 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gamma-aminobutyric acid receptor subunit rho-2

  • GABA(A) receptor subunit rho-2

  • GABA(C) receptor

  • gamma-aminobutyric acid (GABA-A) receptor, subunit rho 2

  • gamma-aminobutyric acid receptor rho2 subunit

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05226 GABRR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gabrr2 NCBI NCBI:2570