Slc6a13 - solute carrier family 6 (neurotransmitter transporter, GABA), member 13 Gene

Mus musculus

Also known as GAT3; Gat2; Gabt3

Gene ID: 14412 | Gene type: protein coding

About Slc6a13

Summary

Enables taurine transmembrane transporter activity. Involved in taurine transport. Located in basolateral plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and liver and biliary system. Orthologous to human SLC6A13 (solute carrier family 6 member 13). [provided by Alliance of Genome Resources, Apr 2022]

Slc6a13 Products(5)

mRNA	Protein	Name
NM_001379107.1	NP_001366036.1	sodium- and chloride-dependent GABA transporter 2 isoform a
NM_001379108.1	NP_001366037.1	sodium- and chloride-dependent GABA transporter 2 isoform b
NM_001409769.1	NP_001396698.1	sodium- and chloride-dependent GABA transporter 2 isoform c
NM_001409772.1	NP_001396701.1	sodium- and chloride-dependent GABA transporter 2 isoform d
NM_144512.3	NP_653095.1	sodium- and chloride-dependent GABA transporter 2 isoform a

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables amino acid:sodium symporter activity	IDA IDA: Inferred from direct assay	8420981	MGI
enables gamma-aminobutyric acid:sodium:chloride symporter activity	IDA IDA: Inferred from direct assay	8420981	MGI
enables taurine transmembrane transporter activity	IMP IMP: Inferred from mutant phenotype	22896705	MGI
enables taurine:sodium symporter activity	IDA IDA: Inferred from direct assay	8420981	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in taurine transmembrane transport	IMP IMP: Inferred from mutant phenotype	22896705	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in basolateral plasma membrane	IDA IDA: Inferred from direct assay	22896705	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	22896705	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

sodium- and chloride-dependent GABA transporter 2

GAT-2	GAT-3
gamma-aminobutyric acid (GABA-A) transporter 3	sodium- and chloride-dependent GABA transporter 3
solute carrier family 6 member 13

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13299	SLC6A13 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc6a13	NCBI	NCBI:6540

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