Slc6a13 - solute carrier family 6 (neurotransmitter transporter, GABA), member 13 Gene

Also Known as GAT3; Gat2; Gabt3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14412

Summary

Enables taurine transmembrane transporter activity. Involved in taurine transport. Located in basolateral plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and liver and biliary system. Orthologous to human SLC6A13 (solute carrier family 6 member 13). [provided by Alliance of Genome Resources, Apr 2022]

Slc6a13 Products (5)

mRNA Protein Name
NM_001379107.1 NP_001366036.1 sodium- and chloride-dependent GABA transporter 2 isoform a
NM_001379108.1 NP_001366037.1 sodium- and chloride-dependent GABA transporter 2 isoform b
NM_001409769.1 NP_001396698.1 sodium- and chloride-dependent GABA transporter 2 isoform c
NM_001409772.1 NP_001396701.1 sodium- and chloride-dependent GABA transporter 2 isoform d
NM_144512.3 NP_653095.1 sodium- and chloride-dependent GABA transporter 2 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables amino acid:sodium symporter activity IDA
IDA: Inferred from direct assay
8420981 MGI
enables gamma-aminobutyric acid:sodium:chloride symporter activity IDA
IDA: Inferred from direct assay
8420981 MGI
enables taurine transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
22896705 MGI
enables taurine:sodium symporter activity IDA
IDA: Inferred from direct assay
8420981 MGI
Biological Process GO Annotation Evidence References Source
involved in taurine transmembrane transport IMP
IMP: Inferred from mutant phenotype
22896705 MGI
Cellular Component GO Annotation Evidence References Source
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
22896705 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
22896705 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium- and chloride-dependent GABA transporter 2

  • GAT-2

  • GAT-3

  • gamma-aminobutyric acid (GABA-A) transporter 3

  • sodium- and chloride-dependent GABA transporter 3

  • solute carrier family 6 member 13

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13299 SLC6A13 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc6a13 NCBI NCBI:6540