Gamt - guanidinoacetate methyltransferase Gene

Also Known as Spintz1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14431

Summary

Predicted to enable guanidinoacetate N-methyltransferase activity and identical protein binding activity. Acts upstream of or within several processes, including creatine biosynthetic process; regulation of growth; and spermatogenesis. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus. Is expressed in pancreas. Used to study guanidinoacetate methyltransferase deficiency. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and guanidinoacetate methyltransferase deficiency. Orthologous to human GAMT (guanidinoacetate N-methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Gamt Products (2)

mRNA Protein Name
NM_001347119.1 NP_001334048.1 guanidinoacetate N-methyltransferase isoform 2
NM_010255.4 NP_034385.1 guanidinoacetate N-methyltransferase isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within animal organ morphogenesis IMP
IMP: Inferred from mutant phenotype
15028668 MGI
acts upstream of or within creatine biosynthetic process IMP
IMP: Inferred from mutant phenotype
15028668 MGI
acts upstream of or within regulation of multicellular organism growth IMP
IMP: Inferred from mutant phenotype
15028668 MGI
acts upstream of or within spermatogenesis IMP
IMP: Inferred from mutant phenotype
15028668 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanidinoacetate N-methyltransferase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05268 GAMT Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18478 Gamt Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24959 Gamt Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gamt NCBI NCBI:2593