Opn1mw - opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan) Gene

Also Known as Gcp; Rsvp; Opn1lw; ML-opsin

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14539

Summary

Predicted to enable G protein-coupled photoreceptor activity and identical protein binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to light stimulus; and phototransduction. Predicted to act upstream of or within protein-chromophore linkage and signal transduction. Located in photoreceptor outer segment. Is expressed in eye; photoreceptor layer; photoreceptor layer outer segment; retina; and retina outer nuclear layer. Used to study blue cone monochromacy. Human ortholog(s) of this gene implicated in blue cone monochromacy and red color blindness. Orthologous to several human genes including OPN1LW (opsin 1, long wave sensitive) and OPN1MW2 (opsin 1, medium wave sensitive 2). [provided by Alliance of Genome Resources, Apr 2022]

Opn1mw Products (1)

mRNA Protein Name
NM_008106.2 NP_032132.1 medium-wave-sensitive opsin 1
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21307337 MGI
Cellular Component GO Annotation Evidence References Source
located in photoreceptor outer segment IDA
IDA: Inferred from direct assay
10725384 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

medium-wave-sensitive opsin 1

  • G/R opsin

  • MWS opsin

  • R/G opsin

  • green LWS photopigment

  • green cone photoreceptor pigment

  • green long wavelength sensitive cone opsin

  • green-sensitive opsin

  • medium wavelength-sensitive cone opsin

  • midwavelength sensitive opsin

  • opsin 1 (cone pigments), l

Orthologs Information

Species Symbol Source ID
Homo sapiens Opn1mw NCBI NCBI:2652