Cblif - cobalamin binding intrinsic factor Gene

Also Known as IF; Gif; INF

Species: Mus musculus

Gene Type: protein coding

Gene ID: 14603

Summary

Predicted to enable cobalamin binding activity. Involved in cobalamin metabolic process. Predicted to be located in apical plasma membrane; endosome; and microvillus. Predicted to be active in extracellular space. Is expressed in stomach and stomach glandular region. Human ortholog(s) of this gene implicated in congenital intrinsic factor deficiency and pernicious anemia. Orthologous to human CBLIF (cobalamin binding intrinsic factor). [provided by Alliance of Genome Resources, Apr 2022]

Cblif Products (1)

mRNA	Protein	Name
NM_008118.3	NP_032144.2	cobalamin binding intrinsic factor precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables cargo receptor ligand activity	IDA IDA: Inferred from direct assay	14321840	MGI
enables cobalamin binding	IDA IDA: Inferred from direct assay	14321840	MGI
enables molecular carrier activity	IDA IDA: Inferred from direct assay	14321840	MGI

Biological Process GO Annotation	Evidence	References	Source
involved in cobalamin transport	IMP IMP: Inferred from mutant phenotype	24911144	MGI

Cellular Component GO Annotation	Evidence	References	Source
is active in extracellular space	IDA IDA: Inferred from direct assay	14321840	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
cobalamin binding intrinsic factor	gastric intrinsic factor intrinsic factor

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01999	CBLIF Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cblif	NCBI	NCBI:2694