2. Gene
  3. Gjb1 - gap junction protein, beta 1 Gene

Gjb1 - gap junction protein, beta 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cx32; Cxng; Cnx32; connexin-32

Gene ID: 14618 | Gene type: protein coding

About Gjb1

Summary

This gene is a member of the Gap Junction Protein (connexin) family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of ions and small molecules between cells. Mutations in a similar gene in human cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Oct 2014]

Gjb1 Products(4)

mRNA Protein Name
NM_001302496.1 NP_001289425.1 gap junction beta-1 protein
NM_001302497.1 NP_001289426.1 gap junction beta-1 protein
NM_001302498.1 NP_001289427.1 gap junction beta-1 protein
NM_008124.3 NP_032150.2 gap junction beta-1 protein
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
20578039 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
20089884 MGI
located in gap junction IDA
IDA: Inferred from direct assay
20089884 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
12829745 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gap junction beta-1 protein

connexin 32

connexin g

connexin-43

gap junction membrane channel protein beta 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05446 GJB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gjb1 NCBI NCBI:2705